Extreme sensitivity of gene expression in human SH-SY5Y neurocytes to ultra-low doses of Gelsemium sempervirens

The study shows that Gelsemium s., a medicinal plant used in traditional remedies and homeopathy, modulates a series of genes involved in neuronal function. A small, but statistically significant, response was detected even to very low doses/high dilutions (up to 30c), indicating that the human neurocyte genome is extremely sensitive to this regulation.

Perioperative Arnica montana for Reduction of Ecchymosis in Rhinoplasty Surgery

Ann Plast Surg. 2015 May 7. [Epub ahead of print] Chaiet SR1, Marcus BC. Author information Abstract BACKGROUND: Studies of homeopathic therapies to decrease post-rhinoplasty ecchymosis have previously used subjective measurements, limiting their clinical significance. Recently, Arnica montana was shown to decrease postoperative ecchymosis after rhytidectomy, using an objective measuring tool. We believe that oral…

Cell sensitivity, non-linearity and inverse effects

Highlights The opinion that the homeopathic principles conflict with scientific laws could be revised. Cell and molecular mechanisms underlying the inversion of drug effects are discussed. Several models have been suggested in the framework of hormesis and paradoxical pharmacology. Low doses or high dilutions of drugs interact with enhanced sensitivities of regulatory systems. A new…