Ginkgo biloba extract improves working memory performance in middle-aged women: role of asymmetry of prefrontal cortex activity during a working memory task.

The results indicate the prefrontal cortex (PFC) plays a role in the physiological cognitive function-enhancing effect of Extraxt of Ginkgo biloba (EGb). EGb might improve working memory function in middle-aged individuals by counteracting the occurrence of aging-related hemispheric asymmetry reduction.